Flunixin Meglumine for Swine Antipyretic Medicine

Product Details
Customization: Available
Varieties: General Disease Prevention Medicine
Component: Chemical Synthetic Drugs
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Number of Employees
87
Year of Establishment
2014-08-13
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Basic Info.

Model NO.
1kg
Type
The First Class
Pharmacodynamic Influential Factors
Combined Medication
Storage Method
Prevent High or LowTemperature
Transport Package
Color Bags
Specification
1KG
Trademark
BOLAI
Origin
China
HS Code
3004909099
Production Capacity
1000000 Per Month

Product Description

Product description
 

Flunixin Meglumine granule  antipyretic medicine for animal

Main composition : Flunixin Meglumine
Character : It is a kind of white or light yellow granule

Pharmacologic action :

pharmacodynamics:       Flunisine meglumine is a strong cyclooxygenase inhibitor with analgesic, antipyretic, anti - inflammatory and anti - rheumatic effects. Analgesic effect is caused by inhibiting the synthesis of peripheral prostaglandins or their nociceptive sensitizers or their combined action, thereby blocking the conduction of nociceptive impulses. The anti-inflammatory effect of peripheral tissues may be caused by inhibiting cyclooxygenase, reducing the formation of prostaglandin precursors, and inhibiting the local inflammatory response caused by other mediators. Flunisine does not affect gastrointestinal motility in horses but may improve hemodynamics in septic shock animals.

pharmacokinetics: After a single intramuscular injection of pigs (2.2mg/kg body weight), the plasma elimination half-life was 3-4 hours, and the peak concentration was 2.94 g/mL, the peak time was 0.4 hours, and the drug could still be detected in the blood after 18 hours of administration. The apparent volume of distribution was 2.0l /kg, and the bioavailability of a single neck injection was 87%

Drug interactions:

(1) When used in conjunction with other nsaids, the adverse effects on the gastrointestinal tract can be exacerbated, such as Ulcer, bleeding

(2) Because of the high binding rate of plasma protein, when combined with other drugs, flunisine meglumine may replace other drugs combined with plasma protein or be itself replaced by other drugs, so that the effect of the drug to be replaced is enhanced, or even produce toxicity

Action and use: Antipyretic and analgesic anti-inflammatory drug,  one dose, each 1kg bodyweight dog, cat 40mg., 1-2 times a day, Continuous use does not exceed 5 days
Precaution:  (1)Use with caution in patients with peptic ulcer  (2)Do not use together  with other nsaids
Specification : calculated by C14H11F3N2O2  5%
Storage : seal well and keep in dark place
Package: 1kg/ 25kg
 Manufacturer: Jiangxi Bolai Pharmacy Co.,Ltd
 
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